While the guests often change, welcoming anyone from Jonathan Ross to Victoria Mitchell, the regulars are host Jimmy Carr, numbers extraordinaire Rachel Riley, wordsmith Susie Dent, and comedians Sean Lock, Jon Richardson and Joe Wilkinson.
The show, which kickstarted back in 2012, is mish-mash between clean-cut Countdown and the riskier 8 Out of 10 Cats game show.
Rachel, who has been dating Strictly professional dancer Pasha Kovalev since 2013, revealed that Jimmy often has crazy parties which has seen her let loose in his hot tub at 4am.
“Each show takes three hours to record and is cut down to 45 minutes,” she told the Mirror.
“So the stuff on the edit floor can be even funnier.”
Rachel explained: “The lawyers have to be involved to make sure some of it doesn’t go out because it would end all of our careers.”
And once the cameras stop rolling the party doesn’t stop for Rachel.
The 32-year-old mathematical whizz, who replaced Carol Vorderman back in 2009, revealed people often go straight from the afterparty to work the following day.